Healthy Person H takes a new drug named ANTICAMPCOLLDUCT that blocks the production of cyclic AMP (cAMP) in collecting duct epithelial cells in response to vasopressin binding to V2 receptors.
A single dose of the latest drug works within one hour and lasts for one week. Which of the following is true for H one day after taking the latest drug?
A. Water permeability of the luminal membranes of the collecting duct epithelial cells will be higher than pre-drug levels.
B. The total unit of AQP2 channels stored in intracellular vesicles will be lower than pre-drug levels.
C. H will make a smaller volume of urine compared with the volume of urine formed prior to taking the drug