Glucokinase
In the fed state, clearance of blood glucose is mainly by liver via glucokinase. Glucokinase, which is an inducible enzyme, removes most of the blood glucose from circulation after a carbohydrate meal. Further, uptake of glucose also takes place in the extra-hepatic tissues (such as muscle, adipose tissue etc.) favoured by insulin. These two mechanisms regulate the blood glucose level in the fed state.