Given the following: You have a [hormone]plasma = 1 µM, which is 60 % bound by plasma proteins. The liver enzyme responsible for metabolizing this hormone does so at a constant rate per [hormone]; i.e., the enzyme follows first-order kinetics. The decay constant, kel, is 0.578. Calculate the t1/2 and then determine the [hormone]plasma 6 half-lives later. Fill in the following table below.
Is this hormone more likely to be H2O-soluble or lipid-soluble?