Assignment Task: A 57-year-old man presents to his primary care physician with concerns about a dark lesion on his upper right arm. He reports that he has always had many freckles, including this one, but thinks there have been changes in size. He denies pain, fever, rash, and shortness of breath.
The biopsy shows atypical cells present in the basal layer of the epidermis and invading the dermis in sheets and nests. The cells have irregular nuclei and prominent nucleoli. The cells are immunoreactive for Mart-1, confirming they are melanocytes.
1. Develop a 1- to 2-page case study analysis, examining the patient signs and symptoms presented in the case study; discussing the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. Need Assignment Help?
2. What role do genetic mutations play in the development of the disease?
3. What is the impact of the disease on the immune system? How do treatment strategies target the pathophysiological mechanisms of the disease?