Explain Zalcitabine and adverse effects
Zalcitabine - Zalcitabine appears to be less effective, less convenient and more toxic than the other NRTIs; it is used rarely.
Adverse effects - Dose-related peripheral neuropathy can be severe and persistent, and is more likely in patients also taking didanosine or stavudine. Other adverse effects contain rash, stomatitis, esophageal ulceration and pancreatitis.