Explain why excessive bleeding occurs with aplastic anemia


a. Explain why bone marrow damage can result in multiple, recurring infections.

b. Explain why excessive bleeding occurs with aplastic anemia.

c. Explain why it is necessary to treat the bone marrow recipient with chemotherapy and radiation before transplant.

c. Explain why vascular occlusions are common in patients with sickle cell disease.

d. Compare sickle cell trait and sickle cell anemia in terms of the genetic factor involved, the amount of HbS present, and the presence of clinical signs.

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