Problem: A 12-year-old female patient presents with her father to the emergency room after a kidney transplant due to ESKD 6 months ago. The father reports that the patient's mother donated the kidney. The patient was doing well after the transplant and was compliant taking the anti-rejection medications as ordered at that time. Recently, the patient missed some of the medication due to her school schedule. The patient has been noticing some edema to her face and hasn't been voiding as much in the last few days. The father brought her into the ER at the direction of the nephrologist. Explain why you think the patient presented the symptoms described.
Identify the genes that may be associated with the development of the disease.
Explain the process of immunosuppression and the effect it has on body systems.