Explain the process of Absorption of Fats?
After digestion, only 25% of triglycerides are broken completely to glycerol and fatty acids. Major digestion product is 2-monoacylglycerol. This is because lipase can hydrolyze ester linkages at the positions 1 and 3 of glycerol preferentially. The 2- monoacylglycerol, fatty acids and 1-monoacylglycerol leave the oily phase 'and diffuse into micelles consisting of bile salts, lecithin and cholesterol into the aqueous phase of intestinal lumen towards brush border of the mucosal cell. The utilization of free fatty acids is by activation of fatty acids and glycerol inside the mucosal cell to resynthesize triacyglycerol. These triacylglycerols and phospholipids, cholesteryl esters, cholesterol and small amount of protein form chylomicrons.