Problem
• Describe the role of "mechanosensing" in the process of bone remodeling. Include all of the cells involved and their functions in this process.
• NASA estimates that astronauts lose 1%-1.5% of bone mineral density in weight bearing bones per month of space flight in microgravity environments without any type of intervention. Luckily, while Jasper is in obit NASA will be implementing both mechanical and chemical preventative measures to help him retain bone density and, therefore, overall bone health. These interventions have been designed through research-based projects you will now analyze.
Exercise Interventions in Space
In 2012, scientists studied the effect of three different exercise programs on the % monthly change of bone density of astronauts in microgravity environments: Mir program (Mir), Interim Resistive Exercise Device - iRED, and Advanced Resistive Exercise Device (ARED).