Question 1
1. Which heavy metal and its salts are a well-known cause of contact dermatitis?
mercury
copper
zinc
nickel
Question 2
1. Which of the following is caused by both cadmium and vinyl chloride?
testicular damage
kidney damage
bone damage
eye damage
Question 3
1. The maximum level of exposure for a compound is known as the:
MDP
MLE
NOAEL
TLV
Question 4
1. The majority of a dose of aspirin is hydrolysed by esterases to __________.
vinyl chloride
ginger jake
salicylic acid
fluoroacetate
Question 5
1. When considering halothane, the exact nature of the toxic metabolite is currently _______.
partially known
not known
not clear
clear
Question 6
1. Which of the following processes of chemical substances via the lungs is efficient and rapid and may lead to systemic effects such as kidney damage?
metabolism
sensitization
discoloration
absorption
Question 7
1. Which compound was formerly used in the rubber industry and is now known as a human carcinogen causing bladder cancer?
vinyl chloride
methylmercury
2-naphthylamine
4-dichlorohexane
Question 8
1. Which is a low molecular weight protein involved with the transport of metals within the body?
metallothionein
chloroaniline
benzidine
aromatic amines
Question 9
1. Although asbestos is chemically inert, the fibers are cytotoxic and will hemolyze _______.
white blood cells
red blood cells
minerals
enzymes
Question 10
1. A bicarbonate ___________ the pH of the blood, causing salicylate to dissociate and diffuse out of tissues such as the brain.
increases
decreases
neutralizes
does nothing with
Question 11
1. Discuss the role of the kidneys and urinary pH in aspirin poisoning.
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Question 12
1. With respect to hydralazine, what is the effect of the HLA type?
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Question 13
1. Identify a least five prescription or over the counter drugs you may be familiar with at home or in your workplace. What are the routes of exposure? As a result of exposure, did you experience any side effects?