Explain Interaction of pyridoxine with Carbohydrates?
Pyridoxine is involved in glyconeogenesis through its action in transaminase reactions. Low levels of pyridoxine impair glucose tolerance. The coenzyme form of vitamin B6 or pyridoxal phosphate or co-decarboxylase is responsible for all non oxidative enzyme amino acid transformations and catalyzes reactions such as decarboxylation transamination, racemization, B6 urinary elimination, amino acid metabolism. PLP has a key role in lipid metabolism and vitamin B6 deficiency lowers body fat, liver lipid levels and impairs degradation of lipids. Administration of riboflavin, pantothenic acid and thiamine provide partial protection against seizures in Vitamin B6 deficient experimental animals.