Explain choice of model and provide support for reliability


Homework: OSHA Toxicology

I. The list of chemicals identified as carcinogens continues to grow. What, in your opinion, are the two best ways to protect yourself from exposure to carcinogens?

II. Reflect on your own thoughts and feelings about animal testing. Do a quick article search on animal testing. Review one article that is pro-animal testing and one article that is anti-animal testing. Discuss two of the pros and two of the cons of animal testing that were discussed in the articles. In researching both sides of the debate, has your perspective shifted any on the animal testing debate? Explain.

III. This unit's assigned reading focuses on chemical-induced mutagens. As you are aware from the reading, not all carcinogens are mutagens. For this homework, compare and contrast a carcinogen that is a mutagen to a carcinogen that is not a mutagen. Find at least four peer-reviewed journal articles published within the last 7 years that discuss the carcinogens and the cancer that each causes.
Compare the means of exposure of each chemical and the type of cancer each causes. Be sure to integrate the perspective and information gathered from each article into a discussion in your own words.
Your literature review must include the following components:

An introduction of your topic of choice (include some background information on the origins of exposure and cancer),the methods used to search for the articles,the results of the articles,

IV. Recent studies support the potential of a drug that is derived from the metal iridium to effectively treat cancer. This experimental drug, Drug ZL105, has not been tested for efficacy and toxicity. Imagine that you are the one responsible for approving or denying the use of this drug within the United States. Your job is to propose the testing that is needed for this drug to be determined as safe and effective for the treatment of cancer in humans. In your research and discussion, you should address the questions below.

What model(s) will you use for testing (i.e., animal, cell cultures, computer simulations)? Explain the choice of model, and provide support for the reliability of the model. Discuss the pros and cons of your choice.

In determining the safety and effectiveness of the drug, would it be necessary to test efficacy, toxicity, and lethality? Explain what each of these tests are for and whether or not one or more of the tests are necessary for your determination.

Provide your thoughts on what information you hope to gather from your tests and whether or not the same protocol should be used for various categories of products such as drugs, cosmetics, and herbal medicines.

Format your homework according to the give formatting requirements:

1. The answer must be double spaced, typed, using Times New Roman font (size 12), with one-inch margins on all sides.

2. The response also includes a cover page containing the title of the homework, the course title, the student's name, and the date. The cover page is not included in the required page length.

3. Also include a reference page. The references and Citations should follow APA format. The reference page is not included in the required page length.

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