Explain about the Niacin (nicotinic acid) deficiency?
Niacin (nicotinic acid) deficiency classically results in pellagva, which is a chronic wasting disease associated with a characteristic erythmatous dermatitis that is bilateral and symmetrical, a dementia after mental changes including insomnia and apathy preceding an overt encephalopathy, and diarrhoea resulting from inflammation of the intestinal mucous surfaces. The disease is, therefore, characterized by 3 D's- dermatitis, diarrhoea and dementia.