Problem:
Analyze and response to the following students discussion post. The pharmacologic agent that I chose to research utilizes genetic engineering in its manufacturing process. It is known by its brand name Remicade and its generic name Infliximab. Remicade functions by reducing inflammation and is indicated for the treatment of various autoimmune conditions, including rheumatoid arthritis, Crohn's disease, ankylosing spondylitis, ulcerative colitis, and psoriasis (Pope, 2024). Remicade first received FDA approval in 1998 for the treatment of autoimmune disorders (Pope, 2024). For rheumatoid arthritis in adults, the initial recommended dose is 3 mg/kg administered as an intravenous infusion, followed by subsequent doses at two and six weeks, and then every 8 weeks as maintenance (Shiel, 2025). The manufacturer of Remicade is Janssen Biotech, Inc., and the estimated cost per month without insurance is approximately $1,300 to $2,500, depending on the dosage required and other factors (Shiel, 2025). Remicade is a monoclonal antibody that is produced through genetic engineering techniques (Pope, 2024). Once administered, Remicade works by binding to and inhibiting tumor necrosis factor-alpha (Pope, 24). This inflammatory protein is involved in many autoimmune diseases. By blocking and neutralizing TNF-alpha, Remicade works to decrease inflammation and slow disease progression in these autoimmune disorders (Pope, 2024). This can lead to effective symptom relief and improved quality of life for those living with these autoimmune diseases (Pope, 2024). Common side effects of Remicade may include headache, abdominal pain, and fever (Shiel, 2025). More severe risks can consist of increased susceptibility to infections and infusion reactions, which may require monitoring or intervention (Shiel, 2025) Need Assignment Help?