Assignment:
Write a review paper containing the most current scientific knowledge on the specific genetic topic.
In your assignment be sure to include information on the basic concepts of genes, potential genes that have been identified/linked with your topic (include chromosome number and location, specific mutations), the gene expression of those specific genes (under-expressed, over expressed, etc.), methods used in their genetic analysis, and the social and political impacts of your genetic topic.
Written Assignment Paper Format- ~4 pages, single spaced, 12-point font, times new roman font, 1 inch margins
Abstract- This is a summary of your research paper. It will highlight ONLY the important information and the critical conclusions. You should keep this section very brief as an abstract is meant to highlight the paper and grab the reader's attention; making them want to read the entire paper. Keep your abstract to 200 to 300 words. I usually recommend writing the abstract last (after you have completed the paper). It is much easier this way as you can read through your completed paper and capture the key points for the abstract. A sample abstract is demonstrated below.
Please look it over so that you are aware of the general format and concept of an abstract.
• Introduction-Briefly discuss the topic you selected. This section is where you will provide background information on your topic. You need to provide the context for the problem/question being addressed and explain how/why this research is important. For example, in this section I would suggest discussing the health implications associated with your topic (for example if you choose a behavioral condition you can discuss the symptoms and effects of that disease on the body. If you choose obesity you can discuss the health effects that obesity can have on the body.
If you choose homosexuality you can discuss the societal reactions and effects on the individual). This section should be about 1 page in length.
• Results of Scientific Research- Briefly discuss the data/information you found in your readings on the current scientific studies on this topic. This is where you want to address the scientific data on your topic. You must include the methods/techniques used to identify potential genes involved, where they are located in the genome (chromosome number/location), the effect on gene expression, the methods used for analysis, number of individuals in study, where the studies were conducted, if any animal models used and what types of experiments were done using these organisms, any important findings or associations that were noted in the scientific articles. This section should be about 1 ½ to 2 pages in length.
• Discussion and Conclusion- This is the area of your paper where you wrap everything up. You need to summarize the paper's findings and generalize their importance in healthcare and in society. You can also highlight any future studies that could be done, mention practical applications of the findings, or discuss ambiguous data. This section should be about 1 page in length.
• References-Please list the sources/sites you used when writing the review paper on your scientific topic.
Citations
1. Harris VM, Koelsch KA, Kurien BT, Harley ITW, Wren JD, Harley JB, Scofield RH. 2019. Characterization of cxorf21 Provides Molecular Insight Into Female-Bias Immune Response in SLE Pathogenesis. Frontiers in Immunology. 10.
2. Migeon BR. 2020. X-linked diseases: susceptible females. Genetics in Medicine: Official Journal of the American College of Medical Genetics. 22(7):1156-1174.
3. Youness A, Miquel C-H, Guéry J-C. 2021. Escape from X Chromosome Inactivation and the Female Predominance in Autoimmune Diseases. International Journal of Molecular Sciences. 22(3):1114.
4. Odhams CA, Roberts AL, Vester SK, Duarte CST, Beales CT, Clarke AJ, Lindinger S, Daffern SJ, Zito A, Chen L, et al. 2019. Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus. Nature Communications. 10(1).