Assignment task: Discuss the changes in thyroid physiology at birth. How does pre-maturity impact these changes? Describe congenital hypothyroidism. Include variations, pathophysiology, screening, and treatment. Differentiate between infantile, childhood and pubertal growth. What are the primary hormones influencing growth? Describe the GH-IGF axis as it pertains to the interaction of hormones which influence growth. Describe the pathophysiology of metabolic syndrome.