Assignment:
Case Study- Enzyme Inhibition and Weight Loss Drugs
As you view the screencast for this case study, use this worksheet to record your answers. You will submit these answers by completing the "Case Study - Enzyme Inhibition & Weight Loss Drugs Worksheet Answers" in Canvas.
1. a. Based on the structure of Alli, what enzyme do you predict it to inhibit?
1.b. Do you predict it to be a competitive or non-competitive inhibitor? Explain your answer.
2. If someone on Alli eats a high-fat meal where does the fat end up, and why?
3. What do the data suggest about Alli® and weight loss? Does Alli® result in more weight loss? Significantly more?
4. a. Why are the side-effects to be expected, and why are they an indication that the drug is working as it should? Be as specific as you can.
4.b. Based on what you know, how could patients taking Alli reduce the occurrence of side-effects? Explain your answer.
5. Why are people taking Alli® advised to take a supplement with Vitamins A, D, E and K? Explain your answer.
6. Write four bullet points that could be part of an ad for Alli®. You need to include at least one bullet point that accurately conveys what weight loss a person taking Alli® can expect, at least one bullet that notes a side effect, and at least on bullet that explains how to avoid/minimize that side effect.