Differential gene expression due to chromosome structure


Could you please help me with an outline for 3 essay questions? I need a peer-reviewed article and points of interest for each of the following topics:

1. Differential gene expression due to chromosome structure and alternative splicing
2. How genes can be used to possibly lend evidence to the theory of evolution
3. How technology could be used to engineer stem cells for human medical treatment

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Biology: Differential gene expression due to chromosome structure
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