Assignment:
1. DNA results from the Jim Jones are given below. Determine the frequency of occurrence and the match probability for this profile.
I have posted a solution to a DNA profile in the course resources. You can use this as a guide for your calculations. Please indicate how you arrived at your answers. You can use an excel spreadsheet or do the calculations by hand.
|
Locus
|
Allele(p)
|
Frequency
|
Allele(q)
|
Frequency
|
|
VWA
|
14
|
0.094
|
15
|
0.111
|
|
TH01
|
5
|
0.002
|
7
|
0.19
|
|
D5S818
|
10
|
0.051
|
11
|
0.361
|
|
D19S433
|
13
|
0.253
|
14
|
0.369
|
|
TPOX
|
8
|
0.535
|
11
|
0.243
|
|
CSF1PO
|
10
|
0.217
|
11
|
0.301
|
|
D3S1358
|
14
|
0.103
|
16
|
0.235
|
|
D7S820
|
10
|
0.243
|
11
|
0.207
|
|
D8S1179
|
12
|
0.185
|
13
|
0.305
|
|
D13S317
|
11
|
0.339
|
12
|
0.248
|
|
D16S539
|
9
|
0.113
|
11
|
0.321
|
|
D18S51
|
13
|
0.127
|
14
|
0.132
|
|
D21S11
|
28
|
0.159
|
30
|
0.278
|
1. Watch Richard III: Solving a 500 Year Old Cold Case Dr Turi King TEDxLeicesterhttps://www.youtube.com/watch?v=oyE9sVs_s58
Read the 2014 Nature article by King et al. (2014), Identification of the remains of King Richard III file in Canvas Module 7. There is a supplemental file that may also be helpful.
Answer the following:
a) When and where did Richard III die and where was he laid to rest?
b) Why was his tomb lost to history?
c) Describe his physical appearance.
d) How was his grave rediscovered?
e) How was he killed?
f) What types of evidence were used and integrated that allowed investigators to confidently determine that the remains were those of Richard III?
g) How is false paternity considered more likely than false maternity?
h) Sum up the physical, genealogical, genetic and historical data the indicate the skeleton is Richard III.
Readings:
Identification of the remains of King Richard III
By Turi E. King, Gloria Gonzalez Fortes