determine sequence weights for the sequences acta, Biology

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determine sequence weights for the sequences acta

Determine sequence weights for the sequences ACTA, ACTT, CGTT, and AGAT in problem 1 by using Thompson, Higgins, and Gibson method

a) compute pairwise distances between sequences (5pts)
b) build phylogenetic the tree using UPGMA method (15pts)
c) derive sequence weights (15pts)

We assumed additive property when constructed UPGMA tree in problem 1.
What is limitation of this assumption?

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