Determine approximate distribution coefficient for pheacetin


The pain reliever phenacetin is soluble in cold water to the extent of 1.0 g/ 1310 mL and soluble in diethyl ether to the extent of 1.0 g/90 mL.

(a) Determine the approximate distribution coefficient for pheacetin in these two solvents.

b) If 50 mg of phenacetin were dissolved in 100 mL of water, how much ether would be required to extract 90% of the phenacetin in a single extraction?

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Chemistry: Determine approximate distribution coefficient for pheacetin
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