Describe what type of hypersensitivity reaction is involved


Problem

A 19 month old infant presents with marked leg swelling, pain, and irritability to walk within 6 hours of receiving booster vaccinations.

Past medical history:

Primary immunizations received at 6, 10, and 14 weeks of age consisting of trivalent oral polio vaccine administered by mouth, hepatitis B virus vaccine, Haemophilus vaccine and diphtheria, pertussis and tetanus vaccine. No other childhood illnesses.

Allergies:

No prior adverse reactions noted

Physical Exam:

Vitals 38.5 degree Celsius

Respiratory rate, blood pressure and Heart Rate: normal for age

Musculoskeletal: marked swelling of the right thigh with tenderness; no discernable edema of the left thigh and no generalized edema
Skin: erythema of right thigh

Question answers should be based on evidence found in readings and from peer-reviewed literature. At least two sources must be used and cited in APA format for each question. Only one source can be a textbook. Resources should generally be within 5 years unless you are explaining the pathophysiology of a disease or providing pertinent background information

Discussion Questions:

o Review the types of hypersensitivity reactions, describe what type of hypersensitivity reaction is involved in this case, and support with evidence.

o According to national guidelines, what would you advise parents regarding further immunization practices?

o Describe the pathophysiological basis for this type of hypersensitivity reaction.

The response must include a reference list. Using Times New Roman 12 pnt font, double-space, one-inch margins, and APA style of writing and citations.

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