Problem: The 'seed and soil' theory proposed by Stephen Paget, says that the distribution of cancers within the body is based on the property of the cancer and the secondary organ where the tumor grows. the place of metastasis of a tumor is dependent on the blood flow of that organ. the secondary growth in an organ depends on the blood flow to that organ and the stromal environment of that organ. the place a cancer metastasizes to is dependent on the properties of the original tumor. Need Assignment Help?