Describe genetic changes found in cancer cells and how


Part 1

Imagine you work at the local museum of natural history, which is opening a wing dedicated to genetics. At the grand opening, scheduled for next month, you will host an event for the community to learn more about genetics and explore the museum. You have been tasked with developing a brochure that provides an overview of genetics to those who attend.

Develop a brochure that may be given to those who attend the grand opening. Use the brochure builder link or another tool of your choice.

Include the following:

• Picture and description of DNA, with a summary of differences between DNA and ribonucleic acid (RNA)

• How DNA is formed into chromosomes

• Explanation of each phase of DNA replication

• Depiction of the transfer of genetic information from DNA to RNA to protein with written explanations of each step

• Description of the role of histones and epigenetics in the organization and gene regulation in chromosomal structures

• Techniques of DNA analysis important to genetic engineering

• Definition of the Human Genome Project including its value in identifying human genetic disorders

Remember that your audience is comprised of members of society and are not experts in biology or genetics.

Use graphics as often as possible to aid in comprehension.

Cite any sources used in your brochure.

Part 2

Write a 1,050- to 1,400-word paper examining the process of gene expression. Include the following:

• Explain the regulation of gene expression in eukaryotic cells.

• Discuss mechanisms by which gene expression may be altered. How do these alterations induce cancer-causing mutations in cell DNA?

• Explain how cancer is formed.

• Describe genetic changes found in cancer cells and how these changes lead to alterations in cell behavior.

• Determine whether proteome data can be utilized in genetic disorder diagnosis.

• Relate the Human Genome Project data to the analysis of cancer genes.

Format your paper consistent with APA guidelines.

Part 3

Refer to the Brochure assignment. The museum is scheduling a speech at the grand opening for a group of high school students in attendance and wants you to write it.

Deliver a 700- to 1,050-word transcript of the speech you would give, including the following:

• Discuss factors that lead to genetic variations in a population by using the Hardy-Weinberg law that describes allele frequencies in a population.

• Explain how animal behaviors, including human behaviors, are governed by genetic inheritance.

• Explain how the laboratory mouse has become a valuable model organism for the study of development and genetics.

o What other animal models are used?

o What contribution(s) has research using Caenorhabditis elegans and Drosophila melanogaster made in the study of animal behavior and population genetics?

• Elaborate on the future of human disease diagnosis using the data from the Human Genome Project.

• Provide sufficient examples to make the speech relevant to high school students.

Part 4

• Review the Recombinant DNA and Ethics activity. To access this activity please log into your student website, and click on the class Bio 410, then click the tab week 5 and then at the very bottom of the page is an assignment titled "Recombinant DNA and Ethics Activity", after you click that assignment link you will see the course materials on the right hand side highlighted in blue, click the link titled "Recombinant DNA and Ethics Activity" then go through each slide to create the following article instructions listed below.

Complete all four sections.

Determine, in each section, whether the items in the presentation are applications of recombinant DNA technology.

• Click on items in each section.

• A pop-up box will appear, asking you whether or not this item is an application of recombinant DNA technology.

• If you click yes, a notepad appears allowing you to type notes about the application and in what way it is used.

• Include any ethical issues that arise out of this application.

• A Microsoft Word document, containing all of your notes, is generated at the end of the activity when you click Print at the bottom of the notepad.

Write a 1,050- to 1,400-word article based on your notes. Include the following:

• Summary of the applications you found

• Discussion about the ethical, legal, and social issues (ELSI) related to the use of recombinant DNA technology

• Discussion on current issues of biotechnology

• Discussion about ethical repercussions of current issues of biotechnology

• Description of four scenes on map

• Scene(s) identified that represent an application of DNA technology

• Scene(s) identified that could be used in an application of DNA technology

• Identification of ethical concerns arising from applications of DNA technology

• Identification of legal concerns arising from applications of DNA technology

• Identification of social concerns arising from applications of DNA technology

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