When the pH is raised to pH 7.4however, polyglutamate spontaneously unfolds to a randomly-coiled conformation. Polyglutamate is a polypeptide made of only L-glutamate residues that forms an α- Helical structure at pH 3. Give a brief explanation that accounts for this behavior. And include a diagram that demonstrates why polyglutamate unfolds at pH 7.4.