Define the Elimination of Vitamin E?
The primary oxidation product of α-tocopherol is α-tocophery quinone that can be conjugated to yield the glucuronate. This glucnronide is excreted in the bile as such or further degraded in the kidneys to α-tocopheronic acid glucusonide and hence excreted in the bile. Those vitamin E homologues not preferentially selected by the hepatic binding proteins are eliminated during the process of nascent VLDL secretion in the liver and probably excreted via the bile. Some vitamin E may also be excreted via skin sebaceous glands.