Define Manganese Metabolism - Micro Minerals?
Intestinal absorption of Mil occurs throughout the length of the small intestine although the exact mechanism of absorption is not clearly established. Ingested Mn is thought to be converted into Mn3+ in the duodenum. Results of the studies suggest that mucosal uptake could be a rapidly saturable process, which appears to be mediated by a high-affinity, low-capacity active transport system.
Available evidence also suggests that mucosal transport occurs through a non-saturable simple diffusion process, It appears that both processes might be involved in the absorption of mineral and may operate simultaneously. Absorption of Mn from the diet is very low. On the basis of Mn retention, it has been estimated that adult humans absorb 4.8% of ingested manganese.