Assignment:
Question 1. Which ONE of the following has shown beneficial effects in the treatment of human colon cancer?
a. Angiostatin
b. Avastin®
c. Endostatin
d. Plasminogen
e. Vascular endothelial growth factor
Question 2. Which ONE statement about antibodies is CORRECT?
a. Antigen binding specificity is due to the hypervariable loops.
b. The Fc fragment is involved in antigen binding.
c. The interactions between antibody and antigen are predominantly
hydrophobic.
d. There are 16 immunoglobulin domains in an intact antibody molecule.
e. There are two variable domains in each molecule.
Question 3. Which ONE of the following targeted agents is used in the treatment of non-Hodgkin's lymphoma?
a. Bevacizumab
b. Erlotinib
c. Imatinib
d. Rituximab
e. Trastuzumab
Question 4. Which ONE of the following targeted agents is a small molecule inhibitor used in the treatment of chronic myeloid leukaemia?
a. Alemtuzumab
b. Cetuximab
c. Dasatinib
d. Ofatumumab
e. Panitumumab
Question 5. Methotrexate is commonly used in combination with which ONE of the following for the treatment of breast cancer?
a. Angiostatin and erlotinib
b. Cyclophosphamide and fluorouracil
c. Doxorubicin and paclitaxel
d. Everolimus and sunitinib
e. Temsirolimus and sorafenib