Consider a trial designed to ·compare cell growth rate using a standard way of preparing a biological specimen (method A) and a new way (method 8). Suppose that four trials done on successive days in the order A. A? 8, B gave .the results 23, 28, 37, 33 and also .that immediately before this trial a .series of preparations on successive days with method A gave the results 25, 23, 27, 31, .32, 35, 40, 38, 38, 33, 27, 21, 19, 24. 17, 15, 14, 19, 23, 22. Using an external reference distribution ω compute the significance level for the null hypothesis ηA = ηB when the alternative is · Is there evidence that B gives higher rates than A.