Compare and contrast acute vs chronic glomerulonephritis


Problem

Case Studies

I. A 23-year-old female presents with urinary frequency absent of infection. The final diagnosis is Diabetes Insipidus. She is treated with dDAVP.

• What would you expect her sodium level would be, high or low? Defend your answer.
• Her osmolarity is elevated. Why?
• Compare and contrast central vs. nephrogenic Diabetes Insipidus.
• Explain the mechanism of dDAVP.

II. A 13-year-old female presents with malaise, facial edema and decreased urinary output. Prior history is positive for strep throat, previously treated. Her work-up revealed severe abnormal lab values. Her final diagnosis is post streptococcal glomerulonephritis.

• What specific lab values would you suspect are abnormal? Defend your answer.
• What is the significance of a positive strep infection?
• Compare and contrast acute vs chronic glomerulonephritis.
• Does glomerulonephritis resolve? Defend your answer.

III. A 19-year-old co ed presents with increasing diarrhea and constipation over the last 2 weeks. She has a history of celiac disease.

• What is the role of immunity and celiac disease?
• What is the effect of gluten on celiac disease?
• Describe the pathophysiology of the diarrhea and constipation.

IV. A 32 year-old-female who recently delivered twins presents with colicky type pain, URQ pain radiating to the shoulder. After workup, she is diagnosed with cholecystitis.

• What is the role of the gallbladder?
• Would you expect her to have nausea and vomiting? Defend your answer.
• Why does the patient have referred pain?
• How do gallstones form?

The response must include a reference list. Using Times New Roman 12 pnt font, double-space, one-inch margins, and APA style of writing and citations.

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