Clotting Disorder - Haemophilia
Haemophilia is a congenital blood clotting disorder caused by the genetic lack/ deficiency of coagulation factor VIII or antihaemophiliac factor and factor IX or christmas factor. Haemophilia due to factor VIIT deficiency is also called as Haemophilia A or (classic haemophilia) and that due to facto IX deficiency is called haemphilia B or (christmas disease).
Haemophilia A and B are inherited as sex linked recessive traits and is manifested in males only. The females carry the hemophiliac trait. Haemophilia is-most frequently inherited by the union of unaffected male and a carrier famale. A haemophiliac male and normal famale produce normal male children and female children who carry the trait. '
Classification of Haemophilia
Haemophilia can be classified into mild, moderate and severe haemophilia depending on level of factor VIII or IX.