Chymotrypsin was able to hydrolyse the substrate


Chymotrypsin was able to hydrolyse the substrate N-benzoyl-L-tyrosine ethyl ester (BTEE) but not able to hydrolyse the substrate p-toluene sulphonyyl-L-arginine methyl ester (TAME).

However the enzyme trypsin was able to hydrolyse both TAME and BTEE substrates, and I was wondering why? And what makes chymotrypsin so much more specific?

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Dissertation: Chymotrypsin was able to hydrolyse the substrate
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