Question 1) Classify Anticonvulsants with examples. Describe mechanism of action and SAof any three classes.
Question 2) Explain the pharmacological actions, chemistry, SAR and metabolism of acetyl choline.
Question 3) Outline the synthesis of the following:
i) Phenyl butazone
ii) Amantadine
iii) Nifedipine
iv) Clonidine
v) Methadone
vi) Phenytoin.
Question 4) Write brief notes on:
i) General anaesthetics
ii) Concept of prodrug
iii) MAO inhibitors
iv) Receptor site theories
Question 5) Classify antihypertensive agents giving suitable examples. Add a note on ACE inhibitors as antihypertensive agent.
Question 6) What are CNS stimulants ? Classify them. Explain the chemistry, SAR, MOA of each class in brief with suitable examples.
Question 7) Define the term ‘Hormones’. Explain the chemistry and biological actions of adrenocorticoids.
Question 8) Write short notes on:
i) Tricyclic antidepressants
ii) Analeptics
iii) Cardiac glycosides
iv) Parkinsonism