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Briefly describe how the secretion of thyroid hormones is

Two women go to their doctor with suspected thyroid disorders to get their thyroid hormone levels tested via their blood serum. The results of those tests are the following:

- Patient 1 shows a low level of Thyroxine (T4) and a high level of TSH.

- Patient 2 shows a high level of Thyroxine (T4) and a low level of TSH.

Both patients are diagnosed with thyroid disorders. Based on these lab results, answer the following:

Briefly describe how the secretion of Thyroid hormones is controlled by a negative feedback system.
What is the diagnosis for Patient 1? What are the symptoms of this disorder?
What is the diagnosis for Patient 2? What are the symptoms of this disorder?

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