Basic host barriers to infection


Describe the journey of a hypothetical enveloped (-) RNA virus through three basic host barriers to infection: Physical b arriers, Innate immune response and adaptive immune response. After overcoming physical barriers, how are viruses recognized at each step, what cells are involved, what soluble factors are involved, which adaptive immune effector cells recognize F and N viral proteins and how is the virus eliminated at each step? For simplicity, let's assume the only the Fusion Protein (F) and Nucleoprotein (N) are recognized by the adaptive immune response (500 words max).

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Biology: Basic host barriers to infection
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