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Based on the ld50 value of dioxins in guinea pigs which was

1- Based on the LD50 value of dioxins in guinea pigs which was extrapolated to humans, dioxins can kill humans. Discuss what this means in toxicological terms?

2- A company wants to do environmental remediation of contaminants. How should they determine the acceptable level of the contaminants for the remediation? What toxicological information would they need for this remediation?

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