As drugs near the end of their patent pharmaceutical


1. The OTC antidiarrheal bismuth subsalicylate (Pepto Bismol®) is recommended:
A. As traveler's diarrhea prophylaxis
B. For all children with diarrhea
C. To be combined with aspirin to be the most effective
D. To be stopped immediately if blackened stool occurs

2. Sadie's adult daughter reports that when Sadie (age 84 years) takes Tylenol PM® (acetaminophen and diphenhydramine) to help her sleep she has "strange dreams" including wandering and thinking she is at her childhood home. You understand:

A. This is a sign of early dementia and she should undergo cognitive testing
B. Sadie is not taking an effective dose to help her stay asleep
C. Sadie is exhibiting signs of an allergic reaction to the diphenhydramine in the product
D. Delirium is a common adverse reaction seen when elderly patients take diphenhydramine

3. As drugs near the end of their patent, pharmaceutical companies may apply for the drug to change to over-the-counter status in order to:
A. Get a new patent for the over-the-counter form of the drug
B. Lower the costs, since most prescription benefit plans do not cover generics
C. Market the drug to a whole new population, as they are able to market to patients instead of just providers
D. Change the drug formulation to extend the patent

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Dissertation: As drugs near the end of their patent pharmaceutical
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