After determining the percent change in the sizes of all


A researcher has taken tissue cultures from 25 subjects. Each culture is divided in half, and a treatment is applied to one of the halves chosen at random. The other half is used as a control. After determining the percent change in the sizes of all culture sections, the researcher calculates the standard error for the treatment-minus-control difference using both the paired t -analysis and the two independent sample (Chapter 2) t -analysis. Finding that the paired t -analysis gives a slightly larger standard error (and gives only half the degrees of freedom), the researcher decides to use the results from the unpaired analysis. Is this legitimate?

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Basic Statistics: After determining the percent change in the sizes of all
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