Statistic Question 1
A UV-vis method is regularly used to determine the drug content of a standard solution giving an average of 450 mg / 100 ml
As part of the quality control process the standard was analysed 6 times, the results for the concentration (mg/dm3) were 460, 450, 472, 460, 464, and 465.
Are these results within the accepted range with 95% confidence?
What can be concluded from the latest set of results?
(16.7% total marks)
Statistic Question 2
The absorption of a drug through skin from two different formulations was investigated using 6 samples of each formulation.
A Franz cell was used with fresh skin for each analysis, the concentrations of the drug in the collecting vessels are tabulated below.
|
Formulation A/ ppm
|
21
|
21
|
24
|
26
|
27
|
27
|
|
Formulation B /ppm
|
18
|
23
|
23
|
25
|
25
|
27
|
Use suitable statistical tests to compare the results from the two formulations.
If the results for a third formulation also needed to be compared, which statistical test would need to be used?