1) Describe Markup languages in detail. Write down the difference among 1D, 2D and 3D structure of a protein molecule.
2) What do you mean by commercial databases? Describe KEGG and CSD in detail.
3) What do you understand by “Linkers” in combinatorial phase synthesis? Write down the solid support material which is used in Solid phase synthesis.
4) What do you mean by “Lead molecule” and structure based library design?
5) Describe chemoinformatics in detail. Write down the application in the field of drug discovery.
6) Write a detailed note on the term “QSAR”.
7) Write down the various file formats which is used in chemical databases. Describe the SMILE notation.
8) What do you mean by internal and Cartesian coordinates? Write your comment on graphical 3D structure of the protein molecule.