Introduction:
Chromone (or 1,4-benzopyrone) is the derivative of benzopyran having a substituted keto group on the pyran ring. The derivatives of Chromone are collectively termed as Chromones. Most, although not all, Chromones are as well phenylpropanoids.
General Chemical reactions of Chromones:
Chromones vary marginally in their chemistry from Coumarins (benzopyran-2-ones) as the carbonyl group is now conjugated by the oxygen atom through the double bond of the heterocycle. This conjugation doesn't involve the benzene ring (figure shown below).
Fig: Chromone Conjugation
As a result, the Chromones are instead more basic and strong acids readily protonate the carbonyl oxygen atoms, making crystalline benzopyrilium salts. Once protonated, the molecule must be resistant to further electrophilic attack, however by fuming nitric acid and concentrated sulphuric acid at between 0°C and room temperature, Chromone provides the 6-nitro derivative (figure shown below). Chromone as well undergoes a Mannish-type reaction (figure shown below) with dimethylamine and formaldehyde (methanal) in hydrogen chloride and ethanol; here the product is 3-(N-N-dimethylaminomethyl) Chromone.
Fig: Reaction of Chromones
Comparatively hard nucleophiles, like Grignard reagents, might attack at the carbonyl carbon, while softer nucleophiles, example: hydroxide ion, join at C-2 by conjugative addition, and this might then cause ring opening (figure shown below).
Fig: Reactions of Chromones with Nucleophiles
Tutorsglobe: A way to secure high grade in your curriculum (Online Tutoring)
Expand your confidence, grow study skills and improve your grades.
Since 2009, Tutorsglobe has proactively helped millions of students to get better grades in school, college or university and score well in competitive tests with live, one-on-one online tutoring.
Using an advanced developed tutoring system providing little or no wait time, the students are connected on-demand with an expert at www.tutorsglobe.com. Students work one-on-one, in real-time with a tutor, communicating and studying using a virtual whiteboard technology. Scientific and mathematical notation, symbols, geometric figures, graphing and freehand drawing can be rendered quickly and easily in the advanced whiteboard.
Free to know our price and packages for online chemistry tutoring. Chat with us or submit request at [email protected]
Organogenesis and Formation of Germ Layers tutorial all along with the key concepts of Orgauogenesis in animal, Product of Three Germ Layer, Formation of germ layers, Formation of early nervous system-neural groove, tube and notochord and Somitogenesis
tutorsglobe.com comparison of direct and indirect methods assignment help-homework help by online techniques of immunofluorescence tutors
It might be useful to make clear the role and composition of the board of directors. The board governs the company for the shareholders and is accountable for promoting their interests.
The Photosynthetic Process tutorial all along with the key concepts of Photochemical Reactions, Cycle Electron Flow, Noncyclic Electron Flow, Biochemical Reactions, C4 Photosynthesis
introduction to physical chemistry tutorial all along with the key concepts of where is physical chemistry used, industries where physical chemistry is used and importance of chemistry in everyday life
tutorsglobe.com market according to time assignment help-homework help by online classification of markets tutors
tutorsglobe.com energy level diagram for molecular orbitals assignment help-homework help by online molecular orbital theory tutors
tutorsglobe.com linux assignment help-homework help by online computer programming tutors
Instrumental Method Analysis tutorial all along with the key concepts of Classical vs Instrumental Techniques, benefits of instrumental techniques, Electrochemical procedure, mass spectroscopy
www.tutorsglobe.com offers message homework help, assignment help, case study, writing homework help, online tutoring assistance by computer science tutors.
tutorsglobe.com biosynthesis of dna assignment help-homework help by online nucleic acid metabolism tutors
carbohydrates tutorial all along with the key concepts of role of carbohydrates, carbohydrates in the diet, simple carbohydrates, complex carbohydrates, sources of carbohydrates, classification of carbohydrates, carbohydrate deficiency diseases and causes of carbohydrate deficiency diseases
linear motion tutorial all along with the key concepts of Motion in a Straight Line and Parameters for describing Motion, Displacement, Velocity, Instantaneous velocity, Average and instantaneous acceleration, Rectilinear motion with constant acceleration, Rectilinear Motion Equations
Statistics in Biology and Agriculture tutorial all along with the key concepts of Statistics and Biostatistics, Use of statistics in biology, Importance of Sample or Sampling, Sampling Methods and Sampling Distribution
Seeking for top-notch Nuclear Physics Assignment Help at feasible prices? Approach us and get benefited!
1958332
Questions Asked
3689
Tutors
1474919
Questions Answered
Start Excelling in your courses, Ask an Expert and get answers for your homework and assignments!!