Synaptic transmission between neurons
How the synaptic transmission between the neurons occurs?
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The propagation of action potential through the axon arrives the region just anterior to the presynaptic membrane resulting in its permeability to the calcium ions in order to alter and these ions to go into the cell. In presynaptic area of the axon there are several neurotransmitter-repleted vesicles which by means of the exocytosis activated through the calcium influx liberate the neurotransmitters in the synaptic cleft. Then the neurotransmitters bind to the specific receptors of postsynaptic membrane. Along with the binding of the neurotransmitters to the postsynaptic receptors the permeability of postsynaptic membrane is changed and depolarization which will lead to first action potential of postsynaptic cell to begin.
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