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Significance of water for an enzymatic activity

What is the significance of water for an enzymatic activity?

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Enzymes, biological catalysts, based on water to reach their substrates and join to them. There is no enzymatic activity devoid of water. Additionally, enzymes based on adequate pH interval to work and the pH is a result of the liberation of hydrogen cations (H+) and hydroxyl anions (OH-) by bases and acids in water solution.

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