1. Where in the body is insulin made? What is the effect of insulin on glucose uptake in muscle? How about in liver? How about in adipose tissue? How about in brain?
2. What would you expect with regards to fasting glucose levels in a patient that had a pancreatic tumor characterized by rapid proliferation and uncontrolled growth of b-cells? How about a pancreatic tumor characterized by rapid proliferation and uncontrolled growth of a-cells? We want more than one-word answers.
3. If a glucose tolerance test were performed on an animal that had been treated several days before with alloxan, what results would you expect? Why?
4. Insulin is generally administered via either intramuscular or subcutaneous (just under the skin) injections. Do you see any potential problems that might be associated with administering insulin in oral tablet form? If so, briefly discuss them. (Hint: think about the type of molecule that is insulin).