Assignment
Case Study: Rheumatoid Arthritis
A 50 year old woman has had rheumatoid arthritis for 3 years and has been taking multiple NSAID's. She has taken corticosteroids a few times during flare ups.
The disease seems to be progressing with stiffness and swelling in her hands and wrists. Examination reveals rheumatoid nodules, synovitis of both wrists and metacarpo-phalangeal joints. This is an indication of an acute exacerbation of rheumatoid arthritis. She is prescribed methotrexate with sulfasalazine and a short course of prednisone.
Questions
1. What is the mechanism of action of prednisone?
2. What is the concern with chronic treatment with glucocorticoids?
3. What is the mechanism of action of methotrexate and sulfasalazine.
4. What are the side effects of methotrexate and sulfasalazine
Format your assignment according to the following formatting requirements:
1. The answer should be typed, double spaced, using Times New Roman font (size 12), with one-inch margins on all sides.
2. The response also includes a cover page containing the title of the assignment, the student's name, the course title, and the date. The cover page is not included in the required page length.
3. Also include a reference page. The Citations and references should follow APA format. The reference page is not included in the required page length.