1) Present the major categories of pathological organisms that can live in host's body.
2) Briefly describe the major factors used for selection of antimicrobial agents.
3) Compare the mechanism of action of bactericidal and bacteriostatic agents.
4) Give your rationale why monitoring of antimicrobial therapy is necessary in clinic.
5) Briefly present the differences in resistance mechanisms of different bacteria to various antibiotics.
6) Briefly present the comparison of therapeutic effects of Beta-lactams and glycopeptides (vancomycin and bacitracin).
7) Briefly present the most important pharmacokinetic parameters of cephalosporins.
8) Explain why aminoglycosides can demonstrate a prolonged postantibiotic effect.
9) Briefly present the most significant pharmacokinetic parameters of antibiotics that inhibit bacterial protein synthesis.
10) Briefly present the mechanism of action of bacteriostatics that affect folic acid synthesis and regeneration.
11) What are major clinical problems related to sulfonamides, trimethoprim fluoroquinolones, nitrofurans and polymyxins use?
12) What are current strategies regarding antimycobacterial agents use?
13) Briefly present the mechanism of action of anti-tuberculosis drugs.
14) Briefly present the mechanism of action of antifungal drugs.
15) Briefly present the benefits of clinical use and differences in pharmacokinetics of antiviral drugs. Give some examples of antiviral drugs that can be used PO, IV or topically.
16) Briefly present the comparison of therapeutic effects and their mechanism of action of antiparasitic drugs.
17) Briefly present the most common clinical problems related to the use of antiviral, antifungal and antiparasitic drugs.