Mechanisms of Contact dermatitis

Mechanisms of Contact dermatitis:

Such drugs or chemicals exerted on the skin behave like haptens.

Whenever these haptens join with skin proteins, that act as carrier they form hapten-carrier complex. Antigen presenting cells [i.e., APC] carry this hapten-carrier complex to the lymphatics, from lymphatics they go to the regional lymph nodes.

In lymph nodes the antigen representing cells present the hapten-carrier complex to the T-cells [CD4T cells]. Such CD4 T cells identify the hapten-carrier complex and discharge lymphokines or interleukins.

Such interleukins activate the T-cells and macrophages that in turn degrade the lesions differing from macules and papules to vesicles that breakdown leaving behind raw weeping regions typical of acute eczematous dermatitis. Such reactions emerge after 24 to 48 hours. This is termed as contact dermatitis.

This hypersensitivity can be identified through Patch Test.


Latest technology based Biology Online Tutoring Assistance

Tutors, at the, take pledge to provide full satisfaction and assurance in Immunology help via online tutoring. Students are getting 100% satisfaction by online tutors across the globe. Here you can get homework help for Immunology, project ideas and tutorials. We provide email based Immunology help. You can join us to ask queries 24x7 with live, experienced and qualified online tutors specialized in Immunology. Through Online Tutoring, you would be able to complete your homework or assignments at your home. Tutors at the TutorsGlobe are committed to provide the best quality online tutoring assistance for Microbiology Homework help and assignment help services. They use their experience, as they have solved thousands of the Biology assignments, which may help you to solve your complex issues of Immunology. TutorsGlobe assure for the best quality compliance to your homework. Compromise with quality is not in our dictionary. If we feel that we are not able to provide the homework help as per the deadline or given instruction by the student, we refund the money of the student without any delay.

2015 ┬ęTutorsGlobe All rights reserved. TutorsGlobe Rated 4.8/5 based on 34139 reviews.