Why would a nonsense mutation be less damaging


Problem

Why would a Nonsense mutation be less damaging if it occurred at the end of the gene rather than the beginning? Gene Sequences Across Species 9. DNA sequences are often used to determine relationships between organisms. DNA sequences that code for a particular gene can vary widely. Organisms that are closely related will have sequences that are similar. Below is a list of sequences for a few organisms: Human: CCA TAG CAC CTA Pig: CCA TGG AAA CGA Chimpanzee: CCA TAA CAC CTA Cricket: CCT AAA GGG ACG --Based on the sequences, which two organisms are most closely related? --An unknown organism is found in the forest, and the gene is sequenced, and found to be C C A T G G A A T C G A , what kind of animal do you think this is? SYNTHESIS Answer each of the following using a single summary sentence. 10. What is the relationship between DNA, codons, and proteins? 11. How does the shape of a protein relate to its function? 12. Explain why some mutations are more harmful than others.

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