Problem:
Question: Why is the eukaryotic proteome so much larger than the number of genes found in an organism?
1. Proteins are large molecules.
2. Differential intron splicing can produce more than one protein product from a gene, and proteins are further posttranslationally modified.
3. Many proteins are made from mitochondrial DNA, and this is not taken into account.
4. The statement is incorrect: the proteome is equal to the number of genes.
Provide the correct answer and justification for your choice.