Why are erythrocytes consider to be enucleate or anucleated


Problem

Chapter 18: Anatomy & Physiology ( McKinley, 4e) McGraw-Hill.

1. What is the composition of plasma? What are gamma-globulins? What percentage of proteins are plasma proteins in plasma? How much of this percentage is due to albumin? What do these plasma proteins do?

2. What is fibrinogen? Fibrin? How much of all blood plasma proteins is from fibrinogen? What do fibrinogen and fibrin do?

3. What are cations? What are anions? What is hematopoiesis? From what "line" of stem cells do erythrocytes form from? (e.g., myeloid? lymphoid?)

4. What are myeloid stem cells? What do they give rise to (form)? What is erythropoiesis and how is it controlled by erythropoietin (EPO)?

5. Where are granulocytes produced? Why are erythrocytes considered to be enucleate or anucleate? Do they have a nucleus at maturity? Why or why not?

6. What is a globin? What are the components of hemoglobin? How many oxygen atoms can be found in a single hemoglobin molecule? What happens to old or damaged erythrocytes? What percentage of erythrocytes "die" every day? What is biliverdin, bilirubin? What are their functions

7. Where are globin proteins broken down? What are the products of globin breakdown and where do their amino acids go?

8. Discuss the various types of anemia, including cycle cell anemia. (Make a list of the different types and their causes). How might you cure cycle cell anemia if it is a "genetic" disease? (look up the recent research online.)

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